OpenNational Institutes of Health

Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

Opportunity number PAR-25-446 · Assistance listing 93.279

Deadline
Aug 21, 2028 · 662 days left
Posted
Sep 10, 2025
Award size
Up to $3M
Total program funding
Not listed
Expected awards
Not listed
Cost sharing
Not required
Funding type
Cooperative agreement
Category
Education, Health

Check this solicitation free

Grantee reads the full announcement and lists every required section, page limit, deadline, scoring criterion and compliance item. Takes about two minutes, no account needed.

About this opportunity

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.

Who can apply

  • City or township governments
  • Public and Indian housing authorities
  • Nonprofits with 501(c)(3) status
  • State governments
  • Federally recognized tribal governments
  • County governments
  • For-profit organizations
  • Public and state universities
  • Special district governments
  • Independent school districts
  • Nonprofits without 501(c)(3) status
  • Other Native American tribal organizations
  • Other (see eligibility)
  • Small businesses
  • Private universities

Other Eligible Applicants include the following:

Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.

Agency contact

NIH Grants Information

grantsinfo@nih.gov
Write this proposal with Grantee
  • Reads the full solicitation and lays out every required section
  • Drafts each section with you, in your words
  • Checks the draft against every requirement before you submit
Official notice on Grants.gov

How to write it

All guides

More from NIH

All NIH funding

Get new funding every Monday

New federal opportunities and upcoming deadlines for NIH and more, in one short email. Free, unsubscribe anytime.

Details from Grants.gov, last updated Sep 10, 2025. Deadlines and requirements can change: always confirm them in the official notice and the agency's page.