OpenNational Institutes of Health

Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)

Opportunity number PAR-27-057 · Assistance listing 93.121

Deadline
Jul 5, 2029 · 979 days left
Posted
Jun 4, 2026
Award size
Up to $500K
Total program funding
Not listed
Expected awards
Not listed
Cost sharing
Not required
Funding type
Cooperative agreement
Category
Health

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About this opportunity

This Notice of Funding Opportunity (NOFO) invites applications for innovative research on the factors that cause human behaviors and the oral-systemic health impacts of those behaviors to enhance health, lengthen life, and reduce illness and disability among people with chronic conditions. Causal hypotheses may include biological, biopsychosocial, congenital, environmental, interpersonal, neurological, psychological, and comorbidity factors that individually, sequentially, or in combination trigger human behaviors and oral-systemic health outcomes, with impacts that may be direct or traceably distal. Applications that propose projects to develop or refine causal hypotheses also are encouraged.

Who can apply

  • State governments
  • Other Native American tribal organizations
  • Nonprofits without 501(c)(3) status
  • Nonprofits with 501(c)(3) status
  • Public and state universities
  • City or township governments
  • Federally recognized tribal governments
  • Public and Indian housing authorities
  • Special district governments
  • County governments
  • For-profit organizations
  • Small businesses
  • Other (see eligibility)
  • Independent school districts
  • Private universities

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Agency contact

National Institute of Dental and Craniofacial Research (NIDCR)

deeranotifications@nidcr.nih.gov
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Details from Grants.gov, last updated Jun 4, 2026. Deadlines and requirements can change: always confirm them in the official notice.