ForecastedNational Institutes of Health

Clinical Trials in Organ Transplantation in Children and Adults

Opportunity number RFA-AI-28-008 · Assistance listing 93.855

Estimated deadline
Sep 30, 2027
Expected posting
Jun 24, 2026
Award size
Not listed
Total program funding
$11.3M
Expected awards
4
Cost sharing
Not required
Funding type
Cooperative agreement
Category
Health

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About this opportunity

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission through the continued support of the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. The goal of the CTOT-CA is to improve the outcome of organ transplantation through clinical trials with mechanistic studies. The CTOT-CA will support multicenter clinical trials, with associated studies of immune mechanisms, in heart, lung, kidney, liver, and intestinal transplantation. The program will also support clinical trials of non-hematopoietic cellular transplantation as replacement therapies; vascularized composite tissue transplantation; and transplantation of bone marrow or mesenchymal stem cells, or of immunologically active cells, as adjuncts to organ transplantation. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Who can apply

  • Other (see eligibility)
  • Public and state universities
  • Small businesses
  • Independent school districts
  • Special district governments
  • Other Native American tribal organizations
  • Federally recognized tribal governments
  • Nonprofits with 501(c)(3) status
  • County governments
  • State governments
  • Public and Indian housing authorities
  • Private universities
  • For-profit organizations
  • City or township governments
  • Nonprofits without 501(c)(3) status

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Agency contact

DAIT Transplantation Branch Clinical Trial Leadership

Please contact via email.

CTOT_CA_U01@mail.nih.gov
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Details from Grants.gov, last updated Jun 24, 2026. Deadlines and requirements can change: always confirm them in the official notice.