ForecastedNational Institutes of Health

Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Opportunity number RFA-CA-28-001 · Assistance listing 93.394

Estimated deadline
Jun 4, 2027
Expected posting
Jul 14, 2026
Award size
Up to $150K
Total program funding
$5.4M
Expected awards
23
Cost sharing
Not required
Funding type
Grant
Category
Health

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About this opportunity

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing to develop innovative technologies for cancer research or clinical care. The emphasis of this NOFO is on early-stage projects proposing proof-of-concept/pilot studies to test the technical feasibility of the proposed method, tool, assay, platform, or instrument.

Well-suited applications must offer a high degree of technical innovation and the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, cancer control, and/or epidemiology. Projects that are in-scope include technologies with new or significantly improved technical capabilities to measure, analyze, model, or interrogate cancer-related systems. These may include, but are not limited to, advanced molecular and cellular analysis platforms, multi-omic and spatial profiling methods, imaging and sensing technologies, immuno-engineering approaches, and innovations in biospecimen processing, modeling, and quality assessment. Technologies proposed for development may have potential for widespread applicability but must be focused in this proposal on cancer applications.

This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

Who can apply

  • For-profit organizations
  • Other (see eligibility)
  • City or township governments
  • Other Native American tribal organizations
  • Federally recognized tribal governments
  • County governments
  • Independent school districts
  • Public and state universities
  • Nonprofits with 501(c)(3) status
  • Private universities
  • State governments
  • Special district governments
  • Nonprofits without 501(c)(3) status
  • Small businesses
  • Public and Indian housing authorities

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Agency contact

IMAT Program Contact

240-255-0917

NCI-IMAT@nih.gov
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Details from Grants.gov, last updated Jul 14, 2026. Deadlines and requirements can change: always confirm them in the official notice.