ForecastedNational Institutes of Health

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

Opportunity number RFA-NS-28-004 · Assistance listing 93.853

Estimated deadline
Mar 4, 2027
Expected posting
Aug 13, 2026
Award size
Not listed
Total program funding
Not listed
Expected awards
15
Cost sharing
Not required
Funding type
Cooperative agreement
Category
Health

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About this opportunity

The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care.

Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.

Who can apply

  • Private universities
  • Other Native American tribal organizations
  • Public and Indian housing authorities
  • County governments
  • State governments
  • Public and state universities
  • Special district governments
  • City or township governments
  • Independent school districts
  • Federally recognized tribal governments
  • For-profit organizations
  • Nonprofits without 501(c)(3) status
  • Other (see eligibility)
  • Nonprofits with 501(c)(3) status
  • Small businesses

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Agency contact

NINDS Department of Emergency Medicine

Please contact via e-mail.

NINDS_SIREN@ninds.nih.gov
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Details from Grants.gov, last updated Aug 13, 2026. Deadlines and requirements can change: always confirm them in the official notice.